Description
Data set includes optimized assay parameters and kinetic characterization for xenopus laevis deiodinase type 3 enzyme, and inhibition activity of 352 ToxCast chemicals against this enzyme.
This dataset is associated with the following publication:
Mayasich, S., J. Korte, J. Denny, P. Hartig, J. Olker, P. Degoey, J. O'Flanagan, S. Degitz, and M. Hornung. Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 73: 105141, (2021).
Resources
| Name | Format | Description | Link |
|---|---|---|---|
| 200714_Mayasich_et_al_Xldio3 screening data.xlsx | XLS | 200714_Mayasich_et_al_Xldio3%20screening%20data.xlsx | Open resource |