Xenpous leavis deiodinase type 3 enzyme activity characterization and chemical screening data
Description
Data set includes optimized assay parameters and kinetic characterization for xenopus laevis deiodinase type 3 enzyme, and inhibition activity of 352 ToxCast chemicals against this enzyme.
This dataset is associated with the following publication:
Mayasich, S., J. Korte, J. Denny, P. Hartig, J. Olker, P. Degoey, J. O'Flanagan, S. Degitz, and M. Hornung. Xenopus laevis and human type 3 iodothyronine deiodinase enzyme cross-species sensitivity to inhibition by ToxCast chemicals. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 73: 105141, (2021).
Resources
| Name |
Format |
Description |
Link |
|
53 |
200714_Mayasich_et_al_Xldio3%20screening%20data.xlsx |
https://pasteur.epa.gov/uploads/10.23719/1504033/200714_Mayasich_et_al_Xldio3%20screening%20data.xlsx |
Tags
- deiodinase
- thyroid
- xenopus
- enzyme-activity