Vapor uptake inhalation data for chloroform in F344 rats
Description
This dataset describes disappearance of chloroform from a vapor uptake chamber with time due to metabolism. The research concentrates on optimization for estimation of metabolic constants using a novel technique.
This dataset is associated with the following publication:
Evans, M., C. Eklund, D. williams, Y. Sey, and J. Simmons. Global Optimization of the Michaelis-Menten parameters using physiologically-based pharmacokinetic (PBPK) modeling and chloroform vapor uptake data in F344 rats. INHALATION TOXICOLOGY. Taylor & Francis, Inc., Philadelphia, PA, USA, 32(3): 97-109, (2020).
Resources
| Name |
Format |
Description |
Link |
|
53 |
EvansMarina_A-z35r_20190702.xlsx |
https://pasteur.epa.gov/uploads/10.23719/1504242/EvansMarina_A-z35r_20190702.xlsx |
Tags
- vapor-uptake-inhalation
- chloroform
- pbpk-model