Secondary screening method for sodium-iodide symporter inhibition utilizing FRTL-5 cells data set
Description
Data pertaining to a NIS-expressing cell line, FRTL-5 and it's screening capabilities for confirming inhibitors of NIS-mediated iodide uptake.
This dataset is associated with the following publication:
Buckalew, A., J. Wang, A. Murr, C. Deisenroth, W. Stewart, T. Stoker, and S. Laws. Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay. Archives of Toxicology. Springer, New York, NY, USA, 94(3): 873-885, (2020).
Resources
| Name |
Format |
Description |
Link |
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53 |
FRTL-5%20dataset%20for%20science-hub.xlsx |
https://pasteur.epa.gov/uploads/10.23719/1518689/FRTL-5%20dataset%20for%20science-hub.xlsx |
Tags
- endocrine-disruption
- high-throughput-in-vitro-screening-assay
- thyroid
- sodium-iodide-symporter