Description
Background
Published formulas for case-control designs provide sample sizes required to determine that a given disease-exposure odds ratio is significantly different from one, adjusting for a potential confounder and possible interaction.
Results
The formulas are extended from one control per case to F controls per case and adjusted for a potential multi-category confounder in unmatched or matched designs. Interactive FORTRAN programs are described which compute the formulas. The effect of potential disease-exposure-confounder interaction may be explored.
Conclusions
Software is now available for computing adjusted sample sizes for case-control designs.
Resources
| Name | Format | Description | Link |
|---|---|---|---|
| Official Government Data Source | HTML | Visit the original government dataset for complete information, documentation, and data access. | Open resource |