Saili_AOP43_Systems Modeling of Developmental Vascular Toxicity
Description
The AOP concept was used to translate ToxCast high-throughput screening data into a ToxPi matrix of 1058 chemicals x 24 features ordered by predicted potential to disrupt angiogenesis.
This dataset is associated with the following publication:
Saili, K., J. Franzosa, N. Baker, R. Ellis-Hutchings, R. Settivari, E. Carney, R. Spencer, T. Zurlinden, N. Kleinstreuer, S. Li, M. Xia, and T. Knudsen. Systems Modeling of Developmental Vascular Toxicity. Current Opinion in Toxicology. Elsevier BV, AMSTERDAM, NETHERLANDS, 15(1): 55-63, (2019).
Resources
| Name |
Format |
Description |
Link |
|
0 |
|
https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Saili/jfranzos |
Tags
- tox21
- virtual-embryo
- 5hpp-33
- vembryo
- angiogenesis
- adverse-outcome-pathway
- tnp-470
- toxcast
- tipping-points
- virtual-tissues