Rodent Research-1 (RR1) National Lab Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data

The Rodent Reasearch-1 National Lab (RR-1 CASIS) experiment was performed to study the effect of microgravity on muscle wasting. RNA, DNA, and protein were purified from RR-1 CASIS (the Center for the Advancement of Science in Space) liver samples. Groups included: Flight (FLT) dissected on-orbit (21 or 22 days after launch); age-matched Ground Controls (GC); and Basal Controls (BC, euthanized at time of launch). RNA-Seq, whole genome BS-Seq (bisulfite sequencing) and proteomic expression profiling were performed.