Reproducibility of organ-level effects in repeat dose animal studies
Description
This work estimates benchmarks for new approach method (NAM) performance in predicting organ-level effects in repeat dose studies of adult animals based on variability in replicate animal studies. Data for Paul Friedman et al., ‘Reproducibility of organ-level effects in repeat dose animal studies’, Computational Toxicology, Vol 28, 100287, Nov 2023, https://doi.org/10.1016/j.comtox.2023.100287.
This dataset is associated with the following publication:
Friedman, K., M. Foster, L.L. Pham, M. Feshuk, S. Watford, J. Wambaugh, R. Judson, R. Setzer, and R. Thomas. Reproducibility of organ-level effects in repeat dose animal studies. Computational Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 28: 100287, (2023).
Resources
| Name |
Format |
Description |
Link |
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0 |
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https://github.com/USEPA/CompTox-Reproducibility-Organ-Effects |
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0 |
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https://clowder.edap-cluster.com/datasets/646d247fe4b08a6b394d2853 |
Tags
- variability
- organ
- toxrefdb
- repeat-dose