Report on Evaluation of the Interaction-based Hazard Index Formula with Data on Trihalomethanes
Description
The endpoints selected for evaluation of the HIINT formula were percent relative liver weight of mice (PcLiv) and the logarithm of ALT [Log(ALT)], where the log transformation was used to help stabilize the increases in variance with dose found in the ALT dataset.
Resources
| Name |
Format |
Description |
Link |
|
10 |
Appendix%20A-9_Interact-HI-THMs_2021-01-31.docx |
https://pasteur.epa.gov/uploads/10.23719/1531675/Appendix%20A-9_Interact-HI-THMs_2021-01-31.docx |
Tags
- interactions
- dose-additivity
- dose-addition
- chemical-mixtures
- chemical-mixtures-risk-assessment
- mixture-effective-dose-estimation
- hazard-index
- binary-interaction-weight-of-evidence