Post Coital DNA Recovery in Minority Proxy Couples, United States, 2014-2018
Description
Introduction and Background. Minorities are less likely to report
rapes. The Post Coital DNA Recovery (PCDR) study (2009-14) subjects were white
(93%) where expanded collection times were not generalizable to minority
populations. Evidence reports health and medical differences between races
necessitating duplication of previous research in minority populations.
Aims.
(1) What is the time period in which it is
possible to collect post-coital DNA in minority women using Y-STR laboratory
methods? and (2) when compared to the former study sample of minority and
non-minority, what are the physiological conditions, factors, or activities in
minority couples that influence post-coital DNA recovery?
Design. The design includes mixed methods duplication
perfected in the first study, embracing descriptive and inferential techniques.
Qualitative research used semi-structured interviews. Aim 1 analysis used PCDR-M
data only. Aim 2 combined data from both PCDR and PCDR-M studies. Combined, DNA
recovery, a binary outcome accounting for repeated methods in population
regression analysis, used Generalized Estimating Equation (GEE) methods.
Fidelity.
The strict criteria for adherence included considerable outreach and
support of study personnel. PCDR and PCDR-M data combined and compared the two
samples, which had specific homogeneity, including same inclusion and
elimination criteria in both studies; fidelity to the validated protocol;
laboratory method and interpretation for inclusion; duplicate statistical
analysis; and interpretation of data. Any variation in key variables met
elimination criteria.
Assumptions and Limitations. Assumptions included (1) motivation is altruistic; (2)
motivation is incentives and coercion for some; (3) negotiating coitus is
difficult and stressful; and (4) similar fidelity and dropout rates. The
limitations included (1) a lack of representation for the diverse experiences
of rape victims; (2) sample size; (3) self-selection bias; (4) protocol adherence;
and (4) advances in laboratory science and DNA kits.
Demographics. Demographic variables included gender, race, and age. Major categories in the dataset included participants' reproductive history, data on female participants' reproductive organs, and childhood abuse.
Resources
| Name |
Format |
Description |
Link |
|
0 |
ICPSR37250.v1 |
https://doi.org/10.3886/ICPSR37250.v1 |
Tags
- sexually-transmitted-disease
- reproductive-history
- genetics-data