Patent AT-E401402-T1: [Translated] PROTEINS INTERACTING WITH SYNDEKAN AND THEIR USE
Description
The invention relates to the identification of a new protein that binds to the cytoplasmic domain of syndecan. This new protein, denominated as "syntenin", contains 298 amino acids and is characterized by a tandem repeat of PDZ-domains that reacts with the C-terminal amino acid sequence of syndecans. The amino-terminal region of syntenin further comprises five tyrosine residues whereas no tyrosine residues are present in the remaining part of the protein. The present invention further discloses a nucleic acid encoding syntenin, a method to screen for components interfering with the syndecan-syntenin interaction, a method for diagnosing Alzheimer's disease, inflammatory diseases, and malignancies and a pharmaceutical composition for healing the latter diseases.
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Access the complete Patent AT-E401402-T1: [Translated] PROTEINS INTERACTING WITH SYNDEKAN AND THEIR USE on the official website. |
https://pubchem.ncbi.nlm.nih.gov/patent/AT-E401402-T1 |
Tags
- patent
- chemistry
- research
- innovation
- pubchem