Patent AT-E40140-T1: [Translated] AROMATASE INHIBITING STEROIDS.
Description
6-Substituted androsta-1,4-diene-3,17-dione derivatives of formula (I) nn whereinn R is (1) the group-N3;n (2) a group nn wherein each of r1 and R2 is, independently, hydrogen or unsaturated C1-C22 alkyl;n (3) a group -NHCOR3 wherein R3 isn (a) hydrogen;n (b) C1-C3 alkoxy or carboxy;n (c) C1-C22 alkyl either unsubstituted or substituted by a carboxy group; orn (d) a group nn wherein R1 and R2 are as defined above; orn (4) a group -NHSO2R4 wherein R4 is unsubstituted C1-C4 alkyl, or phenyl either unsubstituted or substituted by C1-C3 alkyl, halogen or nitro;n and the pharmaceutically acceptable salts thereof are aromatase inhibitors and can be used, e.g. in the treatment of hormone-dependent tumors.
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Access the complete Patent AT-E40140-T1: [Translated] AROMATASE INHIBITING STEROIDS. on the official website. |
https://pubchem.ncbi.nlm.nih.gov/patent/AT-E40140-T1 |
Tags
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- chemistry
- research
- innovation
- pubchem