Patent AT-E401054-T1: [Translated] LIQUID DEPOSIT FORMULATIONS
Description
The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of:a) at least one neutral diacyl lipid and/or at least one tocopherol;b) at least one phospholipid;c) at least one biocompatible, oxygen containing, low viscosity organic solvent;wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The preformulations are suitable for generating parenteral, non-parenteral and topical depot compositions for sustained release of active agents. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament.
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Access the complete Patent AT-E401054-T1: [Translated] LIQUID DEPOSIT FORMULATIONS on the official website. |
https://pubchem.ncbi.nlm.nih.gov/patent/AT-E401054-T1 |
Tags
- patent
- chemistry
- research
- innovation
- pubchem