Description
Whole genome sequences of naturally recombinant European type III and type II x III clones were analyzed While two of the type II x III recombinants showed an intermediate mouse virulence, a type III clone was highly virulent Of the three highly virulent clones, only two showed a virulent ROP18-ROP5 allele combination The mouse virulent type III clone without virulent ROP18-ROP5 allele combination showed the highest level of ROP5 mRNA expression Two genetically similar clones showed apparent differences in virulence and corresponding IL-12 mRNA expression in infected macrophages
Resources
| Name | Format | Description | Link |
|---|---|---|---|
| Unknown Resource | Unknown | Open resource |