Raw ILLUMINA NGS data from study on Mouse virulence of European type III and type II x III-recombinant natural clones of Toxoplasma gondii is not always linked to the ROP18 and ROP5 genotype
Description
Whole genome sequences of naturally recombinant European type III and type II x III clones were analyzed While two of the type II x III recombinants showed an intermediate mouse virulence, a type III clone was highly virulent Of the three highly virulent clones, only two showed a virulent ROP18-ROP5 allele combination The mouse virulent type III clone without virulent ROP18-ROP5 allele combination showed the highest level of ROP5 mRNA expression Two genetically similar clones showed apparent differences in virulence and corresponding IL-12 mRNA expression in infected macrophages
Resources
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http://data.europa.eu/88u/dataset/oai-zenodo-org-7852321 |
Tags
- toxoplasma-gondii;-sexual-recombination;-mouse-virulence;-rop5;-rop16;-rop18;-gra15;-interleukin;-il-12,-il-10;-tnfα