Overview of COVID-19 individual participant data meta-analyses (IPD-MAs)

Individual participant data meta-analyses (IPD-MAs), which include harmonising and analysing participant-level data from related studies, provide several advantages over aggregate data meta-analyses, which pool study-level findings. IPD-MAs inform the design and conduct of randomised clinical trials and have informed the research and public health responses to COVID-19. To identify areas of overlap, we conducted a rapid systematic review of completed or ongoing COVID-19 IPD-MAs. We identified 31 COVID-19 related IPD-MAs, including 5 living IPD-MAs, and found several areas of overlap in study designs, populations, exposures, and outcomes of interest. Details of the 31 identified COVID-19 IPD-MAs are presented in this dataset.