Candida albicans commensalism in the oral mucosa is favoured by limited virulence and metabolic adaptation.

CL was funded by a grant from the Swiss National Science Foundation to SLL (grant N° 310030_166206, www.snf.ch)., KMSV was funded by a grant from the Swiss National Science Foundation to SLL, SD and CdE (grant N° CRSII5_173863, www.snf.ch). and SA and SAV were funded by a grant from the Swiss National Science Foundation to DS, MP and SLL (grants N° 310030_166206, CRSII5_173863 and CRSII3_141848, respectively, www.snf.ch). RFM was funded through the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie action, Innovative Training Network (FunHoMic; grant N° 812969, www.funhomic.eu), to CdE and SLL). LSR's post-doctoral fellowship was funded through a Fondation pour la Recherche Médicale grant to CdE (FRM, DBF20160635719, www.frm.org/). SIB partly funded by the Swiss Federal Government through the Federal Office of Education and Science (https://www.bfs.admin.ch/bfs/en/home/statistics/education-science.html). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.