List of the structures of S-protein in complex with ligands deposited in the Protein Data Bank until the 1st January 2021.
Description
All 131 structures of SARS-CoV-2 S-protein in complex with a ligand released on the PDB until the 1st January 2021 were categorised by ligand type: hACE2, antibody Fab fragments, VHH antibody fragments or de novo designed peptide scaffolds. The ligands’ amino acid sequences, the method by which the structures were determined and their resolution were retrieved from the PDB. Information regarding the ligands' production method, dissociation constants (KD), S-protein segment against which the KD were measured and the determination methods were retrieved from the respective references. The categorisation of ligands by S-protein binding site and listing of S-protein conformation in each structure were achieved by visual analysis of all the structures using molecular visualisation software PyMOL.
Resources
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Description |
Link |
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0 |
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http://data.europa.eu/88u/dataset/oai-zenodo-org-5503855 |
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0 |
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http://data.europa.eu/88u/dataset/oai-zenodo-org-5503855 |
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0 |
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http://data.europa.eu/88u/dataset/oai-zenodo-org-5503855 |
Tags
- spike
- de-novo-design
- ace2
- sars-cov-2
- affinity-ligands