NSCR_Dataset_2020

Description

The University of Turin (UniTO) released the open-access dataset NSCR_Dataset collected for the  NEUROSTEMCELLREPAIR (602278) and NSC-Reconstruct (874758) European stem cell consortia for neural cell replacement, reprogramming and functional brain repair (602278)  (https://www.nsc-reconstruct.com/en/index.do). NSCR-Dataset is a dataset of analysis of histological ex-vivo brain samples and behavioral parameters from Huntington's Disease (HD) rat models, after cell replacement approach of striatal progenitor cells at the site of grafting - the striatum, at different time point (see for details at short time-points: https://www.sciencedirect.com/science/article/pii/S2213671120301089?via%3Dihub). The UniTO team released this dataset publicly. The dataset contains images of brain tissue stained for different cellular and molecular markers, acquired with transmission and confocal microscopes, from which analysis were performed, and the behavioral data obtained every month by testing the HD animals in different motor tasks. High-resolution images have been acquired; the images will be made available.

Resources

Name Format Description Link
0 http://data.europa.eu/88u/dataset/oai-zenodo-org-5158956
0 http://data.europa.eu/88u/dataset/oai-zenodo-org-5158956
0 http://data.europa.eu/88u/dataset/oai-zenodo-org-5158956
0 http://data.europa.eu/88u/dataset/oai-zenodo-org-5158956
0 http://data.europa.eu/88u/dataset/oai-zenodo-org-5158956
0 http://data.europa.eu/88u/dataset/oai-zenodo-org-5158956

Tags

  • striatum
  • open-data
  • rabies-virus-based-synaptic-tracing
  • cell-transplantation
  • human-embryonic-stem-cells
  • regenerative-medicine
  • cell-replacement-therapy
  • medium-spiny-neurons
  • behavioral-assessment
  • open-science
  • huntington-disease
  • brain-graft-integration

Topics

Categories