Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Male Rats

Description

behavioral measures of learning and memory in adult offspring of rats treated with thyroid hormone synthesis inhibitor, propylthiouracil. Electrophysiological measures of 'memory' in form of plasticity model known as long term potentiation (LTP) Molecular changes induced by LTP. This dataset is associated with the following publication: Gilbert , M., K. Sanchez-Huerta, and C. Wood. Mild Thyroid Hormone Insufficiency During Development Compromises Activity-Dependent Neuroplasticity in the Hippocampus of Adult Make Rats. ENDOCRINOLOGY. Endocrine Society, 157(2): 774-87, (2016).

Resources

Name Format Description Link
53 M0710_BDNF%20LTP%20Data.xlsx https://pasteur.epa.gov/uploads/403/M0710_BDNF%20LTP%20Data.xlsx

Tags

  • spatial-learning
  • brain
  • fear-conditioning
  • developmental-hypothyroidism
  • neurotrophins
  • ltp
  • brain-development
  • activity-dependent-plasticity
  • neuroplasticity
  • hippocampus
  • thyroid
  • childrens-health
  • bdnf
  • css

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