Microbial Observatory (ISS-MO): Study of BSL-2 bacterial isolates from the International Space Station

Description

In an on-going Microbial Observatory experimental investigation on the International Space Station (ISS) multiple bacterial isolates of Biosafety Level 2 (BSL-2) were isolated and identified. The antibiotic susceptibility pattern was tested in these BSL-2 isolates for the following antibiotics: cefazolin ciprofloxacin cefoxitin erythromycin gentamycin oxacillin penicillin rifampin tobramycin and many of the BSL-2 isolates showed multiple drug resistance. Among these isolates 21 strains were chosen for whole genome sequencing (WGS) for a possible lead to develop appropriate countermeasures. In addition the genomic data would enable to determine the influence of microgravity on the pathogenicity and virulence in the BSL-2 microorganisms.

Resources

Name Format Description Link
5 https://lsda.jsc.nasa.gov%2Fscripts%2Fexperiment%2Fexper.aspx%3Fexp_index%3D13629
5 https://lsda.jsc.nasa.gov%2Fscripts%2Fmission%2Fmiss.aspx%3Fmis_index%3D355
5 https://osdr.nasa.gov%2Fbio%2Frepo%2Fdata%2Fstudies%2FOSD-67
5 https://lsda.jsc.nasa.gov/scripts/mission/miss.aspx?mis_index=355
5 https://lsda.jsc.nasa.gov/scripts/experiment/exper.aspx?exp_index=13629
5 https://osdr.nasa.gov/bio/repo/data/studies/OSD-67
5 https://lsda.jsc.nasa.gov/scripts/experiment/exper.aspx?exp_index=13629
5 https://lsda.jsc.nasa.gov/scripts/mission/miss.aspx?mis_index=355
5 https://osdr.nasa.gov/bio/repo/data/studies/OSD-67

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