Method development for determination of trace amounts of silicon in hydrofluoric acid digests of biological samples and lung biopsy tissues by ICP-MS

Description

A method was described for determination of trace levels of silicon by inductively coupled plasma mass spectrometry (ICP-MS) from hydrofluoric (HF) digests of biological samples. The volatility of silicon in HF digests was examined with synthetic solutions as well as soil and mine waste samples. A digestion scheme was optimized to achieve complete dissolution, avoid loss of volatile silicon species and produce sample solutions that can be directly analyzed by ICP-MS. The performance of the method performance was validated by analysis of a number plant and tissue certified reference materials for silicon by ICP-MS. The method was then applied to the determination of silicon from lung biopsy tissues obtained from military personnel and coal miners.

Resources

Name Format Description Link
55 The metadata original format https://data.usgs.gov/datacatalog/metadata/USGS.65440eebd34ee4b6e05bee4a.xml
55 Landing page for access to the data https://doi.org/10.5066/P9VLL9VJ

Tags

  • environment
  • method-development
  • geology-geophysics-and-geochemistry-science-center
  • inductively-coupled-plasma-spectrometry
  • elemental-analysis
  • lung-tissue
  • silicon
  • mineral-resources-program
  • gggsc
  • mrp
  • health
  • digestion
  • usgs-65440eebd34ee4b6e05bee4a

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