Measuring Microbial Community-Wide Antibiotic Resistance Propagation via Natural Transformation in the Human Gut Microbiome

Description

This repository includes the raw data, analysis code, and results of a systematic analysis of natural transformation (i.e., horizontal gene transfer; HGT) of bacteria in a naturally occurring microbiome (human stool) following exposure to free extracellular DNA (eDNA) that coded for antibiotic resistance. A full description of this effort is available in the associated publication. 

Resources

Name Format Description Link
READEME file Text This file describes the organization of this data record. Open resource
README Text This READEME file describes the organization this data record. Open resource
Read Me Binary This READEME file describes the organization this data record. Open resource
README Text Open resource
Figure 1 - ddPCR Analysis Binary Analysis code of ddPCR data. Open resource
Text File Text Open resource
Web Resource Binary FIG4-WGS-AnalyzingProcessedReads.Rmd Open resource
Text File Text Open resource
Web Resource Binary FIG5-WGS-AnalyzingProcessedReads.Rmd Open resource
Text File Text Open resource
Data ZIP This compressed folder contains the raw data collected in the analysis of aforementioned samples. This includes CFU count results, ddPCR gene quantification, long-read next-generation sequencing (Nanopore) of isolates, and shotgun metagenomic sequencing characterization of microbiome samples. Open resource
Text File Text Open resource
MS Excel File XLS HGT_STORMS_Checklist.xlsx Open resource
Text File Text Open resource

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