Investigation of peroxisome proliferator-activated receptor delta (ppard)-dependent visual startle response hyperactivity in larval zebrafish exposed to structurally similar Per- and Polyfluoroalkyl Substances (PFAS)

Description

PFHxS, PFOS, and Heptachlor RNA sequencing data. Portions of this dataset are inaccessible because: The files are too large. They can be accessed through the following means: The data can be accessed through the hyperlinks. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190490 https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190009. Format: Raw RNA-sequencing output files (fastq files) for PFOS exposure located https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190490. Metadata is included with the GEO submission. Raw RNA-sequencing output files (fastq files) for PFHxS exposure located https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE190009. Metadata is included with the GEO submission. This dataset is associated with the following publication: Gutsfeld, S., L. Wehmas, I. Omoyeni, N. Schweiger, D. Leuthold, P. Michaelis, X.M. Howey, S. Gaballah, N. Herold, C. Vogs, C. Wood, L. Becker-Bertotto, G. Wu, N. Kluver, W. Busch, S. Scholz, J. Schor, and T. Tal. Investigation of Peroxisome Proliferator-Activated Receptor Genes as Requirements for Visual Startle Response Hyperactivity in Larval Zebrafish Exposed to Structurally Similar Per- and Polyfluoroalkyl Substances (PFAS). ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 132(7): 77007, (2024).

Resources

Name Format Description Link
57 supp_data.zip https://pasteur.epa.gov/uploads/10.23719/1529111/supp_data.zip
53 readme_infosheet.xlsx https://pasteur.epa.gov/uploads/10.23719/1529111/readme_infosheet.xlsx

Tags

  • transcriptomics
  • crispr
  • pfas
  • aop
  • zebrafish

Topics

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