Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies
Description
Dataset for "Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies".
This dataset is associated with the following publication:
Lowe, K., J. Dawson, K. Phillips, J. Minucci, J. Wambaugh, H. Qian, T. Ramanarayanan, P. Egeghy, B. Ingle, R. Brunner, E. Mendez, M. Embry, and C. Tan. Incorporating human exposure information in a weight of evidence approach to inform design of repeated dose animal studies. REGULATORY TOXICOLOGY AND PHARMACOLOGY. Elsevier Science Ltd, New York, NY, USA, 127: 105073, (2021).
Resources
| Name |
Format |
Description |
Link |
|
53 |
kmd_exposure_paper_chemsteer_data_drop_outliers_z4.xlsx |
https://pasteur.epa.gov/uploads/10.23719/1524296/kmd_exposure_paper_chemsteer_data_drop_outliers_z4.xlsx |
Tags
- weight-of-evidence
- kinetically-derived-maximum-dose
- toxicokinetics
- exposure
- top-dose-selection