Implementing in vitro bioactivity data to modernize priority setting of chemical inventories
Description
All of the code used to analyze and report the data as well
as build confidence in the approach is available as a supplementary
RMarkdown report, and a tool to derive PODBioactivity and
PODRead-Across is available as an RShiny web-application.
The data used in the workflow are either available on public databases
or are included in the supplementary material to allow
for reproducibility of results. The results and output of the workflow
(i.e., chemical info, PODs, etc.) are provided in the supplementary
material (available as a download from the journal article).
This dataset is associated with the following publication:
Beal, M., M. Gagne, S. Kulkarni, G. Patlewicz, R. Thomas, and T. Barton-Maclaren. Implementing in vitro Bioactivity Data to Modernize Priority Setting of Chemical Inventories. ALTEX. Society ALTEX Edition, Kuesnacht, SWITZERLAND, 39(1): 123-139, (2022).
Resources
| Name |
Format |
Description |
Link |
|
0 |
|
https://github.com/MarcBeal/HC-ESRAB/tree/master/DSL_Bioactivity_PODs |
Tags
- high-throughput-toxicokinetics
- evidence-based-risk-assessment
- high-throughput-screening
- new-approach-methodologies
- read-across