Impact of Scaling Factor Variability on Risk Relevant Outcomes in Children

Description

This dataset contains physiologically-based (PBPK) model code and parameter settings supporting the manuscript titled "THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM)".

This dataset is associated with the following publication:
Kenyon, E., J. Lipscomb, R. Pegram, B. George, and R. Hines. THE IMPACT OF SCALING FACTOR VARIABILITY ON RISK-RELEVANT PHARMACOKINETIC OUTCOMES IN CHILDREN: A CASE STUDY USING BROMODICHLOROMETHANE (BDCM). TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 167(2): 347-359, (2019).

Resources

Name Format Description Link
ModelFile_BDCM_peds.pdf PDF ModelFile_BDCM_peds.pdf Open resource
ModelParameters_PedsScalingVariability.pdf PDF ModelParameters_PedsScalingVariability.pdf Open resource

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