IMPACT OF E-CIGARETTE FLAVORING AGENTS ON ACTIVITY OF MICROSOMAL RECOMBINANT CYP2A6, THE PRIMARY NICOTINE-METABOLIZING-ENZYME

Description

Most of the data illustrates the effects that some e-cigarette flavoring agents, as well as some of the chemical components of those flavoring agents, directly have on the cytochrome P450 2A6 enzyme activity. This dataset is associated with the following publication: Winters, B., T. Kochar, P. Clapp, I. Jaspers, and M. Madden. Impact of E-Cigarette Flavoring Agents on Activity of Microsomal Recombinant CYP2A6, The Primary Nicotine-Metabolizing-Enzyme. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 33(7): 1689-1697, (2020).

Resources

Name Format Description Link
33 data_summary%20fig%204%20%20%2025nov2019.pdf https://pasteur.epa.gov/uploads/10.23719/1506082/data_summary%20fig%204%20%20%2025nov2019.pdf
33 data_summary%20fig7%20%2025nov2019.pdf https://pasteur.epa.gov/uploads/10.23719/1506082/data_summary%20fig7%20%2025nov2019.pdf
33 data_summary%20fig%203%20%20%2025nov2019.pdf https://pasteur.epa.gov/uploads/10.23719/1506082/data_summary%20fig%203%20%20%2025nov2019.pdf
33 data_summary%20fig%205%20%20%2025nov2019.pdf https://pasteur.epa.gov/uploads/10.23719/1506082/data_summary%20fig%205%20%20%2025nov2019.pdf

Tags

  • high-throughput-in-vitro-screening-assay
  • cytochromep450
  • cellular-volatiles

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