Identification of genes involved in ceramide-dependent neuronal apoptosis using cDNA arrays

Description

A cell-culture model was used to establish a profile of gene expression during the effector phase of ceramide-mediated cell death. Of the 239 genes that met the criteria for differential hybridization, 10 correspond to genes previously involved in C2-ceramide or TNF-α signaling pathways and 20 in neuronal disorders, oncogenesis or more broadly in the regulation of proliferation.

Resources

Name Format Description Link
21 Visit the original government dataset for complete information, documentation, and data access. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC126236/

Tags

  • cell-death
  • neuronal-apoptosis
  • gene-expression
  • nih
  • ceramide-signaling

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