Human BDCM Mulit-Route PBPK Model

Description

This data set contains the code for the BDCM human multi-route model written in the programming language acsl. The final published manuscript is provided since it contains all the model parameters and data (from published literature). This dataset is associated with the following publication: Kenyon , E., T.L. Leavens, C. Eklund , and R. Pegram. Development and Application of a Human PBPK Model for Bromodichloromethane (BDCM) to Investigate Impacts of Multi-Route Exposure. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 36(9): 1095-1111, (2015).

Resources

Name Format Description Link
33 BDCMPBPKMs.pdf https://pasteur.epa.gov/uploads/10.23719/1407542/BDCMPBPKMs.pdf
33 BDCM_inhCSL.pdf https://pasteur.epa.gov/uploads/10.23719/1407542/BDCM_inhCSL.pdf
33 LocalSensitivityAnalysis_BDCMpbpk.pdf https://pasteur.epa.gov/uploads/10.23719/1407542/LocalSensitivityAnalysis_BDCMpbpk.pdf
33 GlobalSensitivityAnalysis_BDCMpbpk.pdf https://pasteur.epa.gov/uploads/10.23719/1407542/GlobalSensitivityAnalysis_BDCMpbpk.pdf
33 VmaxKm_HanesWolfPlot_bdcm.pdf https://pasteur.epa.gov/uploads/10.23719/1407542/VmaxKm_HanesWolfPlot_bdcm.pdf

Tags

  • physiologically-based-pharmacokinetic-model
  • multi-route
  • model-code
  • pbpk
  • disinfection-byproducts
  • acslx
  • bromodichloromethane

Topics

Categories