Human BDCM Mulit-Route PBPK Model

Description

This data set contains the code for the BDCM human multi-route model written in the programming language acsl. The final published manuscript is provided since it contains all the model parameters and data (from published literature).

This dataset is associated with the following publication:
Kenyon , E., T.L. Leavens, C. Eklund , and R. Pegram. Development and Application of a Human PBPK Model for Bromodichloromethane (BDCM) to Investigate Impacts of Multi-Route Exposure. JOURNAL OF APPLIED TOXICOLOGY. John Wiley & Sons, Ltd., Indianapolis, IN, USA, 36(9): 1095-1111, (2015).

Resources

Name Format Description Link
BDCM_inhCSL.pdf PDF BDCM_inhCSL.pdf Open resource
BDCMPBPKMs.pdf PDF BDCMPBPKMs.pdf Open resource
GlobalSensitivityAnalysis_BDCMpbpk.pdf PDF GlobalSensitivityAnalysis_BDCMpbpk.pdf Open resource
LocalSensitivityAnalysis_BDCMpbpk.pdf PDF LocalSensitivityAnalysis_BDCMpbpk.pdf Open resource
VmaxKm_HanesWolfPlot_bdcm.pdf PDF VmaxKm_HanesWolfPlot_bdcm.pdf Open resource

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