HTTK: R Package for High-Throughput Toxicokinetics
Description
Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) . Chemical-specific in vitro data have been obtained from relatively high throughput experiments. Both physiologically-based ("PBTK") and empirical (e.g., one compartment) "TK" models can be parameterized for several hundred chemicals and multiple species. These models are solved efficiently, often using compiled (C-based) code.
This dataset is associated with the following publication:
Pearce , R., C. Strope , W. Setzer , N. Sipes , and J. Wambaugh. (Journal of Statistical Software) HTTK: R Package for High-Throughput Toxicokinetics. Journal of Statistical Software. American Statistical Association, Alexandria, VA, USA, 79(4): 1-26, (2017).
Resources
| Name |
Format |
Description |
Link |
|
21 |
index.html |
https://cran.r-project.org/web/packages/httk/index.html |
Tags
- httk
- high-throughput
- exposure
- pharmacokinetics
- expocast
- toxcast