Generalised Read-Across (GenRA) refinements
Description
These new analysis builds on the baseline GenRA approach and presents a proof of concept of how other contexts of similarity namely physchem can be implemented into a search strategy for identification of analogues and how this impacts performance of read-across. Chemicals Involved: Same ToxRef dataset as used in the original GenRA manuscript.
This dataset is associated with the following publication:
Helman, G., I. Shah, and G. Patlewicz. Extending the Generalised Read-Across approach (GenRA): A systematic analysis of the impact of physicochemical property information on read-across performance. Computational Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 8: 34-50, (2018).
Resources
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Description |
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https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/PatlewiczGrace/Extending_the_Generalised_Read-Across_approach_(GenRA)_A_systematic_analysis_of_the_impact_of_physicochemical_property_information_on_read-across_performance/ |
Tags
- generalised-read-across
- dsstox
- genra
- toxcast
- read-across
- physiochemical-parameters