Evaluation of a Multiplexed, Multispecies Nuclear Receptor Assay for Chemical Hazard Assessment

Description

Table S1. All chemicals and AC50 from invitrodb v3 for human FACTORIAL-TRANS assay endpoints. Table S2. Agreement with OECD reference AR agonists. Table S3. Agreement with OECD reference ER agonists. Table S4. Agreement with OECD reference ER antagonists. Table S5. Summary results of 191 test chemicals AC50 agreements Table S6. Curve fitting parameters for all endpoints. Word File: Supplementary data. This dataset is associated with the following publication: Houck, K., A. Simha, A. Bone, J. Doering, S. Vliet, C. LaLone, A. Medvedev, and S. Makarov. Evaluation of a Multiplexed, Multispecies Nuclear Receptor Assay for Chemical Hazard Assessment. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 72: 105016, (2021).

Resources

Name Format Description Link
10 Supplemental%20Data%2C%20S1.docx https://pasteur.epa.gov/uploads/10.23719/1518765/Supplemental%20Data%2C%20S1.docx
53 TableS6.xlsx https://pasteur.epa.gov/uploads/10.23719/1518765/TableS6.xlsx
53 TableS5.xlsx https://pasteur.epa.gov/uploads/10.23719/1518765/TableS5.xlsx
53 TableS4.xlsx https://pasteur.epa.gov/uploads/10.23719/1518765/TableS4.xlsx
53 TableS3.xlsx https://pasteur.epa.gov/uploads/10.23719/1518765/TableS3.xlsx
53 TableS2.xlsx https://pasteur.epa.gov/uploads/10.23719/1518765/TableS2.xlsx
53 TableS1.xlsx https://pasteur.epa.gov/uploads/10.23719/1518765/TableS1.xlsx

Tags

  • high-throughput-toxicology
  • reporter-gene
  • high-throughput-screening
  • toxcast
  • nuclear-receptor
  • multiplexed-assay
  • zebrafish
  • endocrine-disruptors
  • ecotoxicoloty

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