Effects of deiodinase inhibition on amphibian metamorphosis

Description

This dataset contains in vitro and in vivo biochemical and apical (i.e., growth/development) data pertaining to iodotyrosine deiodinase inhibition in the African clawed frog (Xenopus laevis). This dataset is associated with the following publication: Haselman, J., J. Olker, P. Kosian, J. Korte, J. Denny, J. Tietge, M. Hornung, and S. Degitz. Characterization of the Mechanistic Linkages Between Iodothyronine Deiodinase Inhibition and Impaired Thyroid-Mediated Growth and Development in Xenopus Laevis Using Iopanoic Acid. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 187(1): 139-149, (2022).

Resources

Name Format Description Link
53 Haselman_et_al_2021_IOP_data_SciHub.xlsx https://pasteur.epa.gov/uploads/10.23719/1522991/Haselman_et_al_2021_IOP_data_SciHub.xlsx

Tags

  • endocrine-disruption
  • ecotoxicology
  • adverse-outcome-pathway
  • thyroid

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