DEVELOPMENT OF A SCREENING APPROACH TO DETECT THYROID DISRUPTING CHEMICALS THAT INHIBIT THE HUMAN SODIUM IODIDE SYMPORTER (NIS)

Description

Data pertaining to a NIS-expressing cell line, hNIS-HEK293T-EPA, and its screening capabilities for determining inhibitors of NIS-mediated iodide uptake. This dataset is associated with the following publication: Hallinger, D., A. Murr, A. Buckalew, S. Simmons, T. Stoker, and S. Laws. Development of a Screening Approach to Detect Thyroid Disrupting Chemicals that Inhibit the Human Sodium/Iodide Symporter (NIS). TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 66-78, (2017).

Resources

Name Format Description Link
53 A-jm6k.Data.Completed.by.DRH.20161219.xlsx https://pasteur.epa.gov/uploads/10.23719/1389264/A-jm6k.Data.Completed.by.DRH.20161219.xlsx

Tags

  • chemical-screening
  • thyroid
  • sodium-iodide-symporter
  • endocrine-disruptors

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