Description

The toxicity and bioconcentration of 3 pharmaceuticals (amitriptyline, iopamidol, and sertraline) were examined using multiple life stages (larval, juvenile, and adult) of the unionid mussel Lampsilis siliquoidea. The endpoints examined varied with life stage but included survival, behavior (algal clearance rate, filtering frequency), and oxidative stress. Glochidia and juveniles were more sensitive than adult mussels. However, the compounds examined were not toxic at concentrations detected in the environment. The results suggest that glochidia toxicity could be a screening tool for rapidly assessing the toxicity of chemicals of concern to freshwater mussels. Results were published in a scientific article that can be found here: https://doi.org/10.1002/etc.3683

Resources

Name	Format	Description	Link
View ECCC Data Mart (English)	HTML		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/?lang=en
View ECCC Data Mart (French)	HTML		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/?lang=fr
NSACB_IOP_SER_AMI_AdultMussel_Behaviour_EN_FR.csv	CSV		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/NSACB_IOP_SER_AMI_AdultMussel_Behaviour_EN_FR.csv
NSACB_IOP_SER_AMI_AdultMussel_Takedown_EN_FR.csv	CSV		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/NSACB_IOP_SER_AMI_AdultMussel_Takedown_EN_FR.csv
NSACB_IOP_SER_AMI_JuvenileMussel_Behaviour_EN_FR.csv	CSV		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/NSACB_IOP_SER_AMI_JuvenileMussel_Behaviour_EN_FR.csv
NSACB_IOP_SER_AMI_JuvenileMussel_Takedown_EN_FR.csv	CSV		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/NSACB_IOP_SER_AMI_JuvenileMussel_Takedown_EN_FR.csv
NSACB_IOP_SER_AMI_MusselGlochidia_Viability_EN_FR.csv	CSV		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/NSACB_IOP_SER_AMI_MusselGlochidia_Viability_EN_FR.csv
NSACB_SER_AMI_Mussel_ClearanceRate_EN_FR.csv	CSV		https://data-donnees.ec.gc.ca/data/substances/assess/the-effects-of-pharmaceuticals-on-a-unionid-mussel-lampsilis-siliquoidea-an-examination-of-acute-and-chronic-endpoints-of-toxicity-across-life-stages/NSACB_SER_AMI_Mussel_ClearanceRate_EN_FR.csv

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