Dataset for Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health.
Description
These data represent underlying data generated for the study titled 'Extracellular Vesicles altered by Per- and Polyfluoroalkyl Substance Mixtures: In Vitro Dose-Dependent Release, Chemical Content, and MicroRNA Signatures involved in Liver Health'. Data include extracellular vesicle particle count and size distribution from nanoparticle tracking analysis; microRNA expression data from mRNA sequencing in extracellular vesicles; PFAS signature data from mass spectrometry analysis of isolated HepG2 cell lysates and their secreted extracellular vesicles; in vitro cell viability data.
This dataset is associated with the following publication:
Carberry, C., J. Bangma, L. Koval, D. Keshava, h. Hartwell, M. Sokolsky, R. Fry, and J. Rager. Extracellular vesicles altered by a per- and polyfluoroalkyl substance mixture: in vitro dose-dependent release, chemical content, and microRNA signatures involved in liver health. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 197(2): 155-169, (2024).