Dataset and code for cross species applicability of an AOP network for thyroid hormone system disruption
Description
The data set consists of the following:
1) AOP-Wiki xml downloads from March 2022 used in constructing and evaluating the AOP network.
2) A literature database containing all literature that was cited in the main document. The database also contains additional references that were not explicitly cited in the associated manuscript.
3) R code used for the analyses and visualizations
4) Detailed results from the SeqAPASS tool.
This dataset is associated with the following publication:
Haigis, A., L. Vergauwen, C. LaLone, D. Villeneuve, J. O'Brien, and D. Knapen. Cross-species applicability of an adverse outcome pathway network for thyroid hormone system disruption. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 195(1): 1-27, (2023).
Resources
| Name |
Format |
Description |
Link |
|
53 |
SeqAPASS-details.xlsx |
https://pasteur.epa.gov/uploads/10.23719/1529155/SeqAPASS-details.xlsx |
|
57 |
R-files.zip |
https://pasteur.epa.gov/uploads/10.23719/1529155/R-files.zip |
|
53 |
literature-database.xlsx |
https://pasteur.epa.gov/uploads/10.23719/1529155/literature-database.xlsx |
|
0 |
|
https://clowder.edap-cluster.com/datasets/6495afabe4b08a6b394f8bf2?space=62e913afe4b055edffc06b16 |
Tags
- cross-species-extrapolation
- endocrine-disruption
- thyroid
- adverse-outcome-pathways-aops