Data File 1: Metabolism of cyclic phenones in rainbow trout in vitro assays

Description

Files contain summary reports of chemical and Mass Spectrometry raw and analyzed data used as basis for plot generation and text discussions in the Cyclic phenone metabolism manuscript. File dataset includes a Definition Xcel file listing the supporting files in set. Specifically, the dataset includes individual chemical slice exposure Xcel data summaries for the model cyclic phenones DPK, CBP and CPK as well as well as hepatocyte cytosol exposure data to the same chemicals. Each file contains data organized in labelled tabs that includes General Experimental information, Quantitative and qualitative methods used to process/analyze the raw data for parent and chemical metabolites, chemical mass balances and conclusions. Power point files with the summarized data were presented in the manuscript's Supplemental data. This dataset is associated with the following publication: Serrano, J., M. Tapper, R. Kolanczyk, B. Sheedy, T. Lahren, D. Hammermeister, J. Denny, M. Hornung, A. Kubatova, P. Kosian, J. Voelker, and P. Schmieder. Metabolism of cyclic phenones in rainbow trout in vitro assays. XENOBIOTICA. Taylor & Francis, Inc., Philadelphia, PA, USA, 50(2): 115-131, (2019).

Resources

Name Format Description Link
53 File%20Definition%20Sheet.xlsx https://pasteur.epa.gov/uploads/10.23719/1502613/File%20Definition%20Sheet.xlsx
53 CBP%20slice%20full%20study%20HUB%20File.xlsx https://pasteur.epa.gov/uploads/10.23719/1502613/CBP%20slice%20full%20study%20HUB%20File.xlsx
53 CPK%20slice%20study%20HUB%20File.xlsx https://pasteur.epa.gov/uploads/10.23719/1502613/CPK%20slice%20study%20HUB%20File.xlsx
53 CBP%20DPK%20CPK%20cytosol%20HUB%20File.xlsx https://pasteur.epa.gov/uploads/10.23719/1502613/CBP%20DPK%20CPK%20cytosol%20HUB%20File.xlsx
53 DPK%20full%20study%20HUB%20file.xls https://pasteur.epa.gov/uploads/10.23719/1502613/DPK%20full%20study%20HUB%20file.xls

Tags

  • lc-ms-ms
  • metabolism
  • endocrine-disruption
  • fish-liver-slices
  • gc-ms
  • lc-tof-ms
  • in-vitro-assays
  • estrogen-receptor
  • cyclic-phenones
  • vtg-gene-expression

Topics

Categories