Cytokine, activation marker, and chemokine receptor expression by individual CD4
Description
IL-10, IL-13, IFN-γ, tumor necrosis factor (TNF)-α, LT-α, CD154, and TNF-related activation-induced cytokine (TRANCE) were expressed by 2-20% of rheumatoid arthritis (RA) synovial tissue CD4+ memory T cells, whereas CD4+ cells that produced IL-2, IL-4, or IL-6 were not detected. Expression of none of these molecules by individual CD4+ cells correlated with the exception of TRANCE and IL-10, and TRANCE and TNF-α . A correlation between expression of IL-10 and CCR7, LT-α and CCR6, IFN-γ and CCR5, and TRANCE and CXCR4 was also detected.
Resources
| Name |
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Description |
Link |
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21 |
Visit the original government dataset for complete information, documentation, and data access. |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC17818/ |
Tags
- rheumatoid-arthritis
- cd4-t-cells
- nih
- chemokine-receptors
- cytokine-expression