Description
Whole transcriptomics dose response data is collected and storedthrough public facing Gene Expression Omnibus database.
Raw collected viability/cytotoxicity data for each chemical are collected and presented on separate spreadsheets. Portions of this dataset are inaccessible because: The transcriptomics full data file is too large to be uploaded alone onto ScienceHub, impeding ease of access. They can be accessed through the following means: Raw and processed transcriptomics data is available through Gene Expression Omnibus (GEO, https://www.ncbi.nlm.nih.gov/geo/) under accession GSE199794. Format: The full transcriptomics data set for all chemical conditions tested.
This dataset is associated with the following publication:
Speen, A., J. Murray, T. Krantz, D. Davies, P. Evansky, J. Harrill, L. Everett, J. Bundy, L. Dailey, W. Zander, E. Carlsten, M. Monsees, J. Hill, J. Zavala, and M. Higuchi. Benchmark Dose Modeling Approaches for Volatile Organic Chemicals using a Novel Air-Liquid Interface In Vitro Exposure System. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 188(1): 88-107, (2022).
Resources
| Name | Format | Description | Link |
|---|---|---|---|
| 1,3-butadiene Sample ID and exposure conditions.xlsx | XLS | 1%2C3-butadiene%20Sample%20ID%20and%20exposure%20conditions.xlsx | Open resource |
| 1-Bromopropane Sample ID and Exposure Conditions.xlsx | XLS | 1-Bromopropane%20Sample%20ID%20and%20Exposure%20Conditions.xlsx | Open resource |
| Acetaldehyde Sample ID and Exposure Conditions.xlsx | XLS | Acetaldehyde%20Sample%20ID%20and%20Exposure%20Conditions.xlsx | Open resource |
| Acrolein Sample ID and Exposure Conditions.xlsx | XLS | Acrolein%20Sample%20ID%20and%20Exposure%20Conditions.xlsx | Open resource |
| Carbon Tetrachloride Sample ID and Exposure Conditions.xlsx | XLS | Carbon%20Tetrachloride%20Sample%20ID%20and%20Exposure%20Conditions.xlsx | Open resource |
| Dichloromethane Sample ID and Exposure Conditions1.xlsx | XLS | Dichloromethane%20Sample%20ID%20and%20Exposure%20Conditions1.xlsx | Open resource |
| Formaldehyde Sample ID and Exposure Conditions.xlsx | XLS | Formaldehyde%20Sample%20ID%20and%20Exposure%20Conditions.xlsx | Open resource |
| Trichloroethylene Sample ID and Exposure Conditions.xlsx | XLS | Trichloroethylene%20Sample%20ID%20and%20Exposure%20Conditions.xlsx | Open resource |