A study of gene expression influenced by simulated microgravity in human lymphoblastoid cells
Description
Here in this study we systematically examined the patterns of DNA methylation and hydroxy-methylation with its functional implications in gene regulation for the cultured TK6 lymphoblastoid cells upon exposure to micro-gravity conditions. The results reported here indicate that simulated microgravity alters methylation patterns in a limited way and subsequently the expression of genes involved in stress response like ATF3 FBXO17 MAP3K13 and VCL in TK6 cells. Overall design: Examination of RNA-seq with 2 replicates each for 1 cell type
Resources
| Name |
Format |
Description |
Link |
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21 |
GeneLab Study Page |
https://genelab-data.ndc.nasa.gov/genelab/accession/GLDS-91 |
Tags
- data-processing
- nucleic-acid-extraction
- data-transformation
- treatment-protocol
- library-construction
- growth-protocol
- nucleic-acid-sequencing
- genelab-rnaseq-data-processing-protocol
- microgravity-simulation