A high throughput screening assay for human Thyroperoxidase inhibitors

Description

Dataset for 'A high throughput screening assay for human Thyroperoxidase inhibitors' by Hongyan Dong, et al., a collaboration work with primary authorship at Health Canada. Published in Toxicology in Vitro, Vol 101, 105946, Dec 2024; DOI https://doi.org/10.1016/j.tiv.2024.105946. Supplementary Data File 1: Examples of two solution plates and the resulting assay plate layouts for Single concentration phase. Supplementary Data File 2: The tcpl analyses of all multiple concentration phase data including plots of fitted models, estimates of log AC50 (ga), and hit call. Supplementary Data File 3: Supplementary Tables 1-5. For further data, please contact corresponding author Hongyan Dong at email Hongyan.Dong@hc-sc.gc.ca. This dataset is associated with the following publication: Dong, H., K. Friedman, A. Filiatreault, E. Thomson, and M. Wade. A high throughput screening assay for human Thyroperoxidase inhibitors. TOXICOLOGY IN VITRO. Elsevier Science Ltd, New York, NY, USA, 101: 105946, (2024).

Resources

Name Format Description Link
53 1-s2.0-S0887233324001760-Supplement3.xlsx https://pasteur.epa.gov/uploads/10.23719/1532100/1-s2.0-S0887233324001760-Supplement3.xlsx
33 1-s2.0-S0887233324001760-Supplement2.pdf https://pasteur.epa.gov/uploads/10.23719/1532100/1-s2.0-S0887233324001760-Supplement2.pdf
10 1-s2.0-S0887233324001760-Supplement1.docx https://pasteur.epa.gov/uploads/10.23719/1532100/1-s2.0-S0887233324001760-Supplement1.docx

Tags

  • endocrine-disruption
  • screening-assay
  • thyroid-hormone
  • thyroid-peroxidase

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