A Generic Pharmacokinetic Model for Quantifying Mother-to-Offspring Transfer of Lipophilic Persistent Environmental Chemicals

Description

This data set includes source code files and associated data files that implement a pharmacokinetic (PK) model for lipophilic persistent environmental chemicals (LPECs) that can be used to simulate various exposure scenarios involving pregnant and nursing maternal animals and offspring. The model is described in a manuscript entitled "A Generic Pharmacokinetic Model for Mother-to-Offspring Transfer of Lipophilic Persistent Environmental Chemicals" by Kapraun et al.

Resources

Name Format Description Link
33 RMCSim_install_instructions.pdf https://pasteur.epa.gov/uploads/10.23719/1524467/RMCSim_install_instructions.pdf
57 Kapraun2022_LPEC_PK_model.zip https://pasteur.epa.gov/uploads/10.23719/1524467/Kapraun2022_LPEC_PK_model.zip
33 Kapraun2022_LPEC_PK_model_instructions.pdf https://pasteur.epa.gov/uploads/10.23719/1524467/Kapraun2022_LPEC_PK_model_instructions.pdf

Tags

  • pharmacokinetic-model
  • lipophilic-persistent-environmental-chemical
  • pregnancy
  • childrens-environmental-health
  • lactational-transfer

Topics

Categories