A fulvic acid-like substance participates in the pro-inflammatory effects of cigarette smoke and wood smoke particles

Description

We tested the postulate that 1) a fulvic acid (FA)-like substance is included in cigarette smoke and wood smoke particles and 2) exposure of respiratory epithelial cells to this substance results in a disruption of iron homeostasis associated with both a cell deficiency of the metal and inflammatory response. It was concluded that 1) FA-like substance is included in cigarette smoke and wood smoke particle and 2) respiratory epithelial cell exposure to this substance results in a disruption of iron homeostasis associated with both a cell deficiency of the metal and inflammatory response. This dataset is associated with the following publication: Gonzalez, D., J. Soukup, M. Madden, M. Hays, J. Berntsen, S. Paulson, and A. Ghio. A fulvic acid-like substance participates in the pro-inflammatory effects of cigarette smoke and wood smoke particles.. CHEMICAL RESEARCH IN TOXICOLOGY. American Chemical Society, Washington, DC, USA, 33(4): 999-1009, (2020).

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Name Format Description Link
53 ghioandrew_fulvicacid_fig6A.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig6A.xlsx
53 ghioandrew_fulvicacid_fig8B.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig8B.xlsx
53 ghioandrew_fulvicacid_fig5B.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig5B.xlsx
53 ghioandrew_fulvicacid_fig6B.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig6B.xlsx
53 ghioandrew_fulvicacid_fig7A.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig7A.xlsx
53 ghioandrew_fulvicacid_fig5A.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig5A.xlsx
53 ghioandrew_fulvicacid_fig8A.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig8A.xlsx
53 ghioandrew_fulvicacid_fig7B.xlsx https://pasteur.epa.gov/uploads/10.23719/1504592/ghioandrew_fulvicacid_fig7B.xlsx

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  • air-pollution

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