Summary Safety Review - Antidepressants - Assessing the Potential Risk of Serious Eye Disorder (Angle-Closure Glaucoma)

Health Canada carried out this safety review when it became aware that the FDA was investigating the risk of angle-closure glaucoma linked to antidepressant use. Angle-closure glaucoma is a serious eye disorder where eye fluid drainage is blocked, leading to a sudden increase in the pressure in the eye and causing pain and blurred vision. If not treated immediately, angle-closure glaucoma can lead to permanent vision loss.