Description

Venlafaxine is an antidepressant and anti-anxiety drug that has been detected in municipal wastewater at low micrograms per litre (ug/L) concentrations. In this study, the nest-defense behavior of adult male fathead minnows (Pimephales promelas) was observed in fish exposed for a full lifecycle to venlafaxine nominal concentrations. Nest-defense behaviors quantified were the time taken to contact a dummy intruder fish (on a flexible stick, held near each nest) and the number of contacts made during a 1 minute period. This study is the first to assess reproductive behaviors in fish exposed to an antidepressant over a full lifecycle. Supplemental Information The Chemicals Management Plan (CMP) is a Government of Canada initiative aimed at reducing the risks posed by chemicals to Canadians and their environment. A key element of the Chemicals Management Plan is the monitoring and surveillance of levels of harmful chemicals in Canadians and their environment. Monitoring and surveillance are essential to identify and track exposure to hazards in the environment and associated health implications. Monitoring and surveillance programs provide the basis for making sound and effective public health and environmental health policies and interventions, as well as measuring the efficacy of control measures. In support of the Chemicals Management Plan, monitoring and surveillance initiatives were established to support Health Canada and Environment and Climate Change Canada scientists, in collaboration with external partners and researchers, to advance our knowledge. This initiative has allowed the Government of Canada to increase its commitment to a number of existing monitoring initiatives, as well as to support new efforts. For more information on the Chemicals Management Plan, please visit https://www.canada.ca/en/health-canada/services/chemical-substances/chemicals-management-plan.html

Resources

Name	Format	Description	Link
View ECCC Data Mart (English)	HTML		https://data-donnees.ec.gc.ca/data/substances/monitor/nest-defense-behaviors-in-fathead-minnows-after-lifecycle-exposure-to-the-antidepressant-venlafaxine/
CMP_FatheadMinnow_Venlafaxine_Exposure_NestDefense_EN_FR.csv	CSV		https://data-donnees.ec.gc.ca/data/substances/monitor/nest-defense-behaviors-in-fathead-minnows-after-lifecycle-exposure-to-the-antidepressant-venlafaxine/CMP_FatheadMinnow_Venlafaxine_Exposure_NestDefense_EN_FR.csv
Voir le Dépôt de données d'ECCC (Anglais)	HTML		https://data-donnees.ec.gc.ca/data/substances/monitor/nest-defense-behaviors-in-fathead-minnows-after-lifecycle-exposure-to-the-antidepressant-venlafaxine/?lang=fr
Scientific Publication - Nest-defense behaviors in fathead minnows after lifecycle exposure to the antidepressant venlafaxin	HTML		https://doi.org/10.1016/j.envpol.2017.11.049

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