Toxicity of the pharmaceuticals finasteride and melengestrol acetate to the freshwater mussels Lampsilis siliquoidea and Lampsilis fasciola

The toxicity of pharmaceuticals finasteride (FIN) and melengestrol acetate (MGA) was assessed in freshwater mussels, including an acute (48 h) aqueous tests with glochidia from Lampsilis siliquoidea, a sub-chronic (14 days) sediment test with gravid female Lampsilis fasciola, and chronic (21 and 28 days) sediment tests with juvenile L. siliquoidea. Glochidia viability was assessed in the 48 hour test; behaviour and glochidia viability were assessed in the 14 day test; and survival and burial was assessed in the 21 and 28 day tests.