2017_Prediction_of_H295R_steroidogenesis_Pathway_Perturbation
Description
The objectives of this work were to: 1) develop an integrated analysis of chemical-mediated effects on steroidogenesis in the HT-H295R assay; and, 2) evaluate whether the HT-H295R assay predicts estrogen and androgen production specifically via comparison with the OECD-validated H295R assay.
This dataset is associated with the following publication:
Haggard, D., A. Karmaus, M. Martin, R. Judson, W. Setzer, and K. Paul-Friedman. (Toxicological Sciences) High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis. TOXICOLOGICAL SCIENCES. Society of Toxicology, RESTON, VA, 162(2): 509-534, (2018).
Resources
| Name |
Format |
Description |
Link |
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0 |
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https://github.com/USEPA/CompTox-ToxCast-EDSPsteroidogenesis |
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0 |
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https://gaftp.epa.gov/COMPTOX/NCCT_Publication_Data/Haggard/2017_Prediction_of_H295R_steroidogenesis_Pathway_Perturbation/ |
Tags
- actor
- steroidogenesi
- toxcast
- edsp21