Description

The toxicity and modes of action of prioritized flame retardants were evaluated in aquatic organisms. The effects of the organophosphorous-containing flame retardant tris (2-butoxyethyl) phosphate (TBOEP) were measured in Daphnia magna after chronic (21-d) and multigenerational exposure (3 generations) as part of a multi-level biological approach including specific gene transcription measured by qRT-PCR, enzyme activity, and life-history endpoints (i.e., survival, growth and reproduction). The effects of two emerging brominated flame retardants, 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE) and 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB) were measured in diet exposed juvenile rainbow trout (Oncorhynchus mykiss) after 48-h and 28-d of exposure. Gene transcription was measured by RNA-sequencing and qRT-PCR at the end of the exposure, as well as specific protein biomarker activity.

Resources

Name	Format	Description	Link
Multigenerational effects of TBOEP in Daphnia magna	Unknown		https://open.canada.ca/data/en/dataset/42782066-ea05-4372-a3dd-dc39c7a7306a
Chronic effects of TBOEP in Daphnia magna	Unknown		https://open.canada.ca/data/en/dataset/79fb74f8-dea4-4f99-8e4e-5bc90354a697
Effects of brominated emerging flame retardants in juvenile rainbow trout	Unknown		https://open.canada.ca/data/en/dataset/9cfc7c72-0f0c-474c-87d4-74602fa845da
Multigenerational effects of TBOEP in Daphnia magna	Unknown		https://open.canada.ca/data/fr/dataset/42782066-ea05-4372-a3dd-dc39c7a7306a
Chronic effects of TBOEP in Daphnia magna	Unknown		https://open.canada.ca/data/fr/dataset/79fb74f8-dea4-4f99-8e4e-5bc90354a697
Effects of brominated emerging flame retardants in juvenile rainbow trout	Unknown		https://open.canada.ca/data/fr/dataset/9cfc7c72-0f0c-474c-87d4-74602fa845da

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